Talk to the Veterans Crisis Line now
U.S. flag
An official website of the United States government

Office of Research & Development

print icon sign up for VA Research updates

CSP Coordinating Center - Hines, IL

Originally called the "VA Midwest Research Support Center", the Hines CSP Coordinating Center supported single and multi-center clinical research conducted in VA hospitals in the Midwest Region. In the early 1970s, a special emphasis was placed on conducting cooperative studies in the VA system and the center was redesignated as a Cooperative Studies Program (CSP) Coordinating Center.

The Hines CSP Coordinating Center has been involved in many key studies and research efforts for VA and organizations such as the American College of Surgeons and the National Institutes of Health. Recent and historic studies coordinated by the Hines CSP Coordinating Center have been reported in the following publications:

  • Plaque Regression and Endothelial Progenitor Cell Mobilization with Intensive Lipid Elimination Regimen (PREMIER). Authors: Banerjee S, Luo P, Reda DJ, et al. (Circ Cardiovasc Interv,,13:e008933, 2020)
  • Comparing two randomized deep brain stimulation trials for Parkinson’s disease. Authors: Deuschl G, Follett KA, Luo P et al. (J Neurosurg 132:1376-1384, 2020)
  • Intensive Glucose Control in Patients with Type 2 Diabetes – 15 year Follow-up. Authors: Reaven PD, Emanuele NV, Wiitala WL, Bahn GD, Reda DJ, et al. (N Engl J Med, 380:2215-2224, 2019.
  • Outcomes of the Veterans Affairs Low Vision Intervention Trial II (LOVIT II): A Randomized Clinical Trial. Authors: Stelmack JA, Tang XC, Wei Y et al. (JAMA Opthalmol, 135:96-104, 2017)
  • Pallidal versus Subthalamic Deep-Brain Stimulation for Parkinson’s Disease. Authors: Follett KA, Weaver FM, Stern M, Hur K, Harris CL, Luo P et al. (N Engl J Med 326:2077-2091, 2010)
  • Glucose Control and Vascular Complications in Veterans with Type 2 Diabetes Authors: Duckworth W, Abraira C, Moritz T et al. (N Engl J Med, 360:129-139, 2009)
  • Glucosamine, Chondroitin Sulfate, and the Two in Combination for Painful Knee Osteoarthritis: The Glucosamine/chondroitin Arthritis Intervention Trial (GAIT). Authors: Clegg, DO, Reda DJ, Harris CL et al. (N Engl J Med, 354:795-808, 2006)
  • Amiodarone versus Sotalol for Atrial Fibrillation. Authors: Singh BN, Singh, SN, Reda DJ et al. (N Engl J Med, 352:1861-1872, 2005)
  • Coronary Artery Revascularization Prior to Major Elective Vascular Surgery and Long-term Outcome: The Coronary Artery Revascularization Prophylaxis (CARP) trial. Authors: McFalls EO, Ward HB, Moritz TE et al. (N Engl J Med, 351:2795-2804, 2004)
  • Open Mesh Versus Laparoscopic Mesh Repair of Inguinal Hernia. Authors: Neumayer L, Giobbie-Hurder A, Jonasson O et al. (N Engl J Med, 350:1819-1827, 2004)
  • Efficacy of 3 Commonly Used Hearing Aid Circuits: A Crossover Trial. Authors: Larson VC, Williams DW, Henderson WG et al. (J Am Med Assoc, 284:1806-1813, 2000)
  • Subcutaneous Compared With Intravenous Epoetin in Patients Receiving Hemodialysis. Authors: Kaufman JS, Reda DJ, Fye CL et al (N Engl J Med, 339:578-583, 1998)
  • Comparison of Clozapine and Haloperidol in Hospitalized Patients with Refractory Schizophrenia. Authors: Rosenheck R, Cramer J, Xu W et al. (N Engl J Med, 337: 809-815, 1997)
  • Comparison of the Implantable Insulin Pump with Multiple Dose Insulin in the Treatment of Non-Insulin-Dependent Diabetes Mellitus: The Veterans Affairs Implantable Insulin Pump Study. Authors: Saudek CD, Duckworth WC, Giobbie-Hurder A et al (J Am Med Assoc, 276:1322-1327, 1996).
  • A Comparison of Transurethral Resection with Watchful Waiting in Men with Moderate Symptoms of Benign Prostatic Hyperplasia. Authors: Wasson JH, Reda DJ, Bruskewitz RC et al (N Engl J Med, 332:75-79, 1995)
  • A Comparison of Outcomes in Men 11 Years After Heart-Valve Replacement with a Mechanical Valve or Bioprosthesis. Authors: Hammermeister KE, Sethi GK, Henderson WG et al. (N Engl J Med, 328:1289-96, 1993)
  • A Prospective, Randomized Study of Cochlear Implants. Authors: Cohen NL, Waltzman SB, Fisher SG. (N Engl J Med: 328:233-237, 1993)
  • Single-drug therapy for hypertension in men: a comparison of six antihypertensive agents with Placebo. Authors: Materson BJ, Reda DJ, Cushman WC (N Engl J Med, 328:914-921, 1993)
  • Randomized Trial of Induction Chemotherapy for Preservation of the Larynx in Patients with Advanced Laryngeal Cancer. Authors: Department of Veterans Affairs Laryngeal Cancer Study Group. (N Engl J Med, 324: 1685-1690, 1991)
  • Intrapleural Tetracycline for the Prevention of Recurrent Spontaneous Pneumothorax. Authors: Lights RW, O'Hara VS, Moritz T et al. (J Am Med Assoc, 264: 2224-2230, 1990)
  • A Twin Study of the Effects of the Vietnam Era on Posttraumatic Stress Disorder. Authors: Goldberg J, True WR, Eisen SA et al (J Am Med Assoc, 263:1227-1232, 1990)

The center expanded its mission in 2007 and now provides coordinating center and study oversight support for a variety of clinical trials in the Clinical Science Research and Development Service (CSR&D). The center coordinates and manages central data monitoring committees for CSR&D-funded clinical trials. The center also supports the development, conduct and analysis of studies funded by the Cooperative Clinical Trial Awards Program, a Merit Review Program of CSR&D. The goal of this program is to provide an opportunity for investigators to collaborate with VA CSP on smaller clinical trials, with the Hines CSP Coordinating Center providing clinical research methods support, and administrative and budgetary management. Such support includes proposal development assistance, study implementation, central coordination of study conduct, data management, interim statistical analyses and study monitoring, and final statistical analyses for study publications. The types of clinical trials appropriate for this program include: 1) trials typically funded by the Merit Review Award Program that require the resources of the CSP Center in order to assure proper conduct of the trial, and 2) single or multi-center clinical trials that are smaller in scope and budget than those typically funded by CSP.

Facilities and Staff

The Hines CSP Coordinating Center is located on the campus of the Hines VA Medical Center, 12 miles west of downtown Chicago. Personnel who contribute to the design, conduct, and management of CSP studies include biostatisticians, computer programmers, health economists, project managers, research assistants, a quality assurance officer and administrative support staff.

One unique aspect of the Hines CSP Coordinating Center is its physical proximity to the VA Health Services Research & Development Center, VA Rehabilitation Centers for Patients with Spinal Cord Injuries and Visual Impairments, and the VA Information Resource Center at the Hines VA Medical Center. This arrangement enables collaborations between the centers on different areas of research that are important in the care provided to the Veteran population. One result of this collaboration was the creation of the Center for Cooperative Studies in Health Services (CCSHS) during the 1990s. The CCSHS conducted multi-center cooperative studies in health services research and was later integrated as part of the Hines CSP Coordinating Center.

Academic Affiliations

Key Personnel

Tamara Haegerich, PhD
Acting Director, Hines CSPCC

Joyce Gilroy
Associate Director, Administrative Operations


Cooperative Studies Program
Coordinating Center (151K)
Hines VA Hospital
5000 South 5th Avenue, Building 1, Room B240
Hines, IL 60141-3030

Phone: (708) 202-5853
Fax: (708) 202-2116

Questions about the R&D website? Email the Web Team

Any health information on this website is strictly for informational purposes and is not intended as medical advice. It should not be used to diagnose or treat any condition.