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Project Number: | I01BX005322-01A1 |
| Title: | Remote injury responses after AKI |
| Principal Investigator: | Andreas Herrlich |
| Location: | St Louis, MO |
| Congressional District Code: | 1 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | July 2021 - June 2025 |
| FY 2021 Funding Amount: | $90,102 |
| Total Award Amount (all years): |
$704,379 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: PROJECT SUMMARY ABSTRACT The overall goal of our research is to develop novel strategies to treat secondary complications of acute kidney injury (AKI). Remote acute lung injury (ALI) is a frequent and often lethal complication of acute kidney injury (AKI) that lacks therapies. Molecular mechanisms of AKI-ALI are incompletely understood, but circulating inflammatory cytokines, e.g. tumor-necrosis-factor (TNF) and T cells have been implicated. Which specific kidney cell types release and which lun... |