Office of Research & Development |
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Project Number: | I01RX003124-01A2 |
Title: | Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans with Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome) |
Principal Investigator: | Susmita Chowdhuri |
Location: | Allen Park, MI |
Congressional District Code: | 13 |
Research Service: | Rehabilitation R&D |
Project Period: | April 2020 - March 2025 |
FY 2021 Funding Amount: | $10,953 |
Total Award Amount (all years): |
$1,195,441 |
Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Cognitive dysfunction in the aging and elderly Veteran population confers a risk for increased mortality. Cognitive deficits are prevalent in neurodegenerative disorders, like Alzheimer’s disease, stroke, and depression. More recently, obstructive sleep apnea (OSA) has been recognized as a factor contributing to cognitive deficits via intermittent hypoxia and sleep fragmentation. Moreover, chronic lung disease, particularly COPD, is also thought to be related to cognitive decline, possibly throu... |