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Funded Project Details - FY2021




Project Number:

I01RX003124-01A2
Title: Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans with Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)
Principal Investigator:

Susmita Chowdhuri

Location: Allen Park, MI
Congressional District Code: 13
Research Service: Rehabilitation R&D
Project Period: April 2020 - March 2025
FY 2021 Funding Amount: $10,953
Total Award Amount
(all years):
$1,195,441
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Cognitive dysfunction in the aging and elderly Veteran population confers a risk for increased mortality. Cognitive deficits are prevalent in neurodegenerative disorders, like Alzheimer’s disease, stroke, and depression. More recently, obstructive sleep apnea (OSA) has been recognized as a factor contributing to cognitive deficits via intermittent hypoxia and sleep fragmentation. Moreover, chronic lung disease, particularly COPD, is also thought to be related to cognitive decline, possibly throu...



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