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Project Number: | I01BX004447-01 |
| Title: | Pathogenesis of Helicobacter pylori infection |
| Principal Investigator: | Timothy L. Cover |
| Location: | Nashville, TN |
| Congressional District Code: | 5 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | April 2019 - March 2023 |
| FY 2021 Funding Amount: | $156,800 |
| Total Award Amount (all years): |
$709,500 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Helicobacter pylori is a Gram-negative bacterium that colonizes the human stomach. H. pylori infection is associated with an increased risk of cancer of the distal stomach, as well as peptic ulcer disease. The World Health Organization has classified H. pylori as a type I carcinogen, and gastric cancer is the third leading cause of cancer-related death worldwide. The long-term goals of this work are to understand the molecular mechanisms that allow H. pylori to persistently colonize the human ga... |