Office of Research & Development |
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Project Number: | I01RX002484-01A2 |
Title: | Identifying novel proteins in injured nerves that promote functional regeneration |
Principal Investigator: | Wendy M. Campana |
Location: | San Diego, CA |
Congressional District Code: | 52 |
Research Service: | Rehabilitation R&D |
Project Period: | November 2018 - October 2022 |
FY 2021 Funding Amount: | $275,000 |
Total Award Amount (all years): |
$1,100,000 |
Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: It is increasingly apparent that Schwann cells (SCs) in the peripheral nervous system (PNS) function as a unit with neurons to regulate sensory function. When the PNS is injured, SCs become activated for repair. This involves dramatic SC phenotypic transformation. If this process is abnormal or inhibited, peripheral nerve in- jury may result in chronic debilitating pain, a problem observed in the general population, including numerous Veterans. Treatment options for chronic neuropathic pain are... |