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Project Number: | I01BX003821-01A1 |
| Title: | Immunogenetic control of autoimmune biliary disease |
| Principal Investigator: | William M Ridgway |
| Location: | Martinez, CA |
| Congressional District Code: | 1 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | April 2018 - September 2022 |
| FY 2021 Funding Amount: | $156,800 |
| Total Award Amount (all years): |
$828,236 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Primary biliary cholangitis (PBC) is an incurable autoimmune biliary disease (“ABD”) in which the immune system destroys bile ducts by targeting cholangiocytes. Many immune based therapies have been applied to PBC, but none have been successful and the disease is currently incurable. Progress in finding new therapies for PBC has been blocked because the clinical symptoms of disease often arise many years after initiation of disease; thus data derived from human patients has not permitted fundame... |