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Project Number: | I01BX003856-01A1 |
| Title: | Development of Near Infrared Fluorescence-Guided Surgical Navigation and Tumor Specific Photoimmunotherapy for Improved Outcomes for GI Cancers |
| Principal Investigator: | Michael Bouvet |
| Location: | San Diego, CA |
| Congressional District Code: | 52 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | October 2017 - September 2021 |
| FY 2021 Funding Amount: | $165,000 |
| Total Award Amount (all years): |
$770,000 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: The ability of the surgeon to accurately visualize tumor margins and identify metastases is necessary for the success of any cancer operation. Fluorescence imaging, because of its high sensitivity, low cost, portability, and real-time capabilities has great potential to improve surgical outcomes. Our laboratories have pioneered the use of fluorophore-conjugated tumor-specific antibodies for detection and resection of GI cancers in orthotopic mouse models with highly improved outcomes. Thus far,... |