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Funded Project Details - FY2021




Project Number:

I01BX003725-01A1
Title: The role of the androgen receptor in insulin secretion
Principal Investigator:

Franck Mauvais-Jarvis

Location: New Orleans, LA
Congressional District Code: 2
Research Service: Biomedical Laboratory R&D
Project Period: October 2017 - September 2022
FY 2021 Funding Amount: $156,800
Total Award Amount
(all years):
$770,000
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

In the Veterans Healthcare System, aging men with testosterone deficiency and men on androgen depletion therapy for prostate cancer are at increased risk of developing type 2 diabetes (T2D). Although studies examining this issue have focused on the role of testosterone deficiency as a risk factor for insulin resistance, this approach ignores the role of testosterone deficiency as a potential cause of pancreatic β–cell dysfunction in men. Although it has been established that testosterone action...



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