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Funded Project Details - FY2021




Project Number:

I01BX001923-05
Title: Role of Cholesterol in Age-related Decline in Steroidogenesis
Principal Investigator:

Salman Azhar

Location: Palo Alto, CA
Congressional District Code: 14
Research Service: Biomedical Laboratory R&D
Project Period: October 2016 - March 2021
FY 2021 Funding Amount: $0
Total Award Amount
(all years):
$752,277
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Numerous cross-sectional and longitudinal studies have established that circulating levels of testosterone decline with age in men, and this decline has been associated with parallel age-related metabolic and pathophysiological changes such as increased fat mass, cardiovascular risk, and incidence of frailty, depression, osteopenia, osteoporosis, insulin resistance and type 2 diabetes and decreased muscle/bone mass, and sexual function. Likewise, aging of the human ovary also results in a gradua...



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