Office of Research & Development |
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Project Number: | I01BX001957-05 |
Title: | Targeting the Bone Microenvironment to Reduce Tumor-induced Bone Disease |
Principal Investigator: | Julie A Sterling |
Location: | Nashville, TN |
Congressional District Code: | 5 |
Research Service: | Biomedical Laboratory R&D |
Project Period: | July 2017 - June 2022 |
FY 2021 Funding Amount: | $262,873 |
Total Award Amount (all years): |
$1,193,047 |
Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Tumor-induced bone disease frequently occurs in patients suffering from some of the most common malignancies (prostate, breast, lung) in the general population and the Veteran population. While the tumor microenvironment is known to support tumor growth and bone destruction, the details of these interactions remain unclear. Despite the well-defined role of bone marrow derived cells in supporting tumor growth and metastasis in soft tissue sites, surprisingly little is known about their contributi... |