GPR109A and Parkinson's Disease: Role of Niacin in Outcome Measures
Congressional District Code:
November 2015 -
FY 2021 Funding Amount:
Total Award Amount (all years):
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DESCRIPTION (provided by applicant): Project Summary/Abstract We are excited to observe significant differences in the GPR109A levels in the white blood cells (macrophages) of Parkinson's disease (PD) patients and control individuals. Moreover, we observed similar changes in the GPR109A expressions in the substantia nigra regions that co-localize with the microglia of the PD patients and age-matched controls. We are the first lab to denote these changes. GPR109A is an anti- inflammatory...