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Project Number: | I01BX005628-01 |
| Title: | BMPR2 mutations, Neointimal Transformation and Pulmonary Arterial Hypertension |
| Principal Investigator: | Mark R Nicolls |
| Location: | Palo Alto, CA |
| Congressional District Code: | 18 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | July 2021 - June 2025 |
| FY 2021 Funding Amount: | $89,148 |
| Total Award Amount (all years): |
$706,376 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Patients served by the Veterans Health Administration who have chronic cardiopulmonary conditions are at high risk for death because of pulmonary hypertension (PH). A particularly dangerous form of PH, referred to as pulmonary arterial hypertension (PAH), is a vascular disease with high prevalence and poor survival among US veterans. PAH is characterized by gene variants, chronic inflammation and an occlusive remodeling of the vascular intima (neointima). Heterozygous germline mutations in BMPR2... |