Talk to the Veterans Crisis Line now
U.S. flag
An official website of the United States government
ORD only    All VA Research websites

Office of Research & Development

print icon sign up for VA Research updates

Funded Project Details - FY2021




Project Number:

I01BX005628-01
Title: BMPR2 mutations, Neointimal Transformation and Pulmonary Arterial Hypertension
Principal Investigator:

Mark R Nicolls

Location: Palo Alto, CA
Congressional District Code: 18
Research Service: Biomedical Laboratory R&D
Project Period: July 2021 - June 2025
FY 2021 Funding Amount: $89,148
Total Award Amount
(all years):
$706,376
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Patients served by the Veterans Health Administration who have chronic cardiopulmonary conditions are at high risk for death because of pulmonary hypertension (PH). A particularly dangerous form of PH, referred to as pulmonary arterial hypertension (PAH), is a vascular disease with high prevalence and poor survival among US veterans. PAH is characterized by gene variants, chronic inflammation and an occlusive remodeling of the vascular intima (neointima). Heterozygous germline mutations in BMPR2...



Questions about the R&D website? Email the Web Team.

Any health information on this website is strictly for informational purposes and is not intended as medical advice. It should not be used to diagnose or treat any condition.