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Project Number: | I01BX003671-05A1 |
| Title: | Caveolin-Mediated Neuroplasticity in Alzheimer's Disease and in Human Neurons Harboring EOFAD Mutations |
| Principal Investigator: | Brian P. Head |
| Location: | San Diego, CA |
| Congressional District Code: | 52 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | April 2021 - March 2025 |
| FY 2023 Funding Amount: | $354,211 |
| Total Award Amount (all years): |
$1,596,027 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Age is one of the highest risk factors for Alzheimer’s disease (AD) with approximately 5.5 million people age 65 and older living with AD in the U.S., a number estimated to grow to 13 million by 2050. AD is closely associated with decreased neuronal signaling and loss of synapses [and mitochondrial dysfunction]. The increasing number of individuals and rising healthcare costs associated with AD are further compounded by a growing population of younger Veterans, who have increased risk of AD... |