Evaluating the interaction of the immune system and inflammation on the progression of blast-mediatedneurodegeneration.
Matthew M Harper
Iowa City, IA
Congressional District Code:
March 2021 -
FY 2021 Funding Amount:
Total Award Amount (all years):
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt:
Traumatic brain injury (TBI) is a leading cause of death, accounting for ~30% of all injury deaths in America, with over 2 million Americans acquiring some form of TBI. Approximately 20% of current service members have experienced some form of TBI. Many recent injuries have come in the form of exposures to blast from improvised explosive devices. Blast TBI triggers an activation of the immune system, generation of auto- antibodies, as well as infiltration of circulating immune cells into the cen...