Office of Research & Development |
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Project Number: | IK6BX005391-01 |
Title: | BLRD Merit Review Research Career Scientist (RCS) Award (IK6) |
Principal Investigator: | Jin Chen |
Location: | Nashville, TN |
Congressional District Code: | 5 |
Research Service: | Biomedical Laboratory R&D |
Project Period: | October 2020 - September 2027 |
FY 2021 Funding Amount: | $149,213 |
Total Award Amount (all years): |
$1,054,255 |
Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Project Summary/Abstract The goals of my research programs are to elucidate molecular mechanisms of tumor angiogenesis, cancer metabolism, and anti-tumor immunity, and to translate our discoveries towards improved cancer therapy. During this RCS award period I will continue to: (1) Targeting mTOR signaling pathways in lung cancer subtypes that are refractory to current targeted therapies. We demonstrated previously that mTOR is a common signaling node downstream of “bypass” kinases, and targetin... |