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Funded Project Details - FY2021




Project Number:

I01BX004896-01A2
Title: Translational Study of Blast mTBI Effects on Locus Ceruleus-Cerebellar Network Structure and Function
Principal Investigator:

James s Meabon

Location: Seattle, WA
Congressional District Code: 9
Research Service: Biomedical Laboratory R&D
Project Period: October 2020 - September 2024
FY 2021 Funding Amount: $291,800
Total Award Amount
(all years):
$1,257,888
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Mild traumatic brain injuries (mTBIs or concussions) caused by blast overpressure from exploding ordnance are the “signature injuries” of the wars in Iraq and Afghanistan. Postconcussive symptoms are common and often persist for years after Veterans have returned from deployment(s); however, the neuropathobiology underlying these symptoms is poorly understood. Our published and preliminary studies demonstrate in a battlefield-relevant mouse model of blast mTBI, in living Veterans with repetitive...



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