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Project Number: | I01BX005466-01 |
| Title: | Covid-19: Fast-tracking treatment by exploiting the steroid hormone receptor/TMPRSS2 axis |
| Principal Investigator: | Kerry Burnstein |
| Location: | Miami, FL |
| Congressional District Code: | 24 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | April 2021 - March 2023 |
| FY 2021 Funding Amount: | $140,612 |
| Total Award Amount (all years): |
$449,226 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: COVID-19 poses a tremendous health threat, particularly to individuals overrepresented in the US Veteran community. COVID-19 mortality is greater in men than in women; while this disparity is at least partially due to factors such as higher rates of smoking, a hormonal link is likely and can be rapidly tested therapeutically by repurposing existing drugs. The viral etiologic agent of COVID-19, SARS-CoV-2 (CoV-2), attaches to human airway epithelium via the viral spike (S) protein, which binds to... |