Office of Research & Development |
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Project Number: | I21RX003459-01A1 |
Title: | Treatment of the Chronic Blast-induced PTSD Phenotype with Capsaicin |
Principal Investigator: | Miguel A. Gama Sosa |
Location: | Bronx, NY |
Congressional District Code: | 13 |
Research Service: | Rehabilitation R&D |
Project Period: | December 2020 - November 2022 |
FY 2021 Funding Amount: | $83,334 |
Total Award Amount (all years): |
$200,000 |
Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Summary Blast-related traumatic brain injury (TBI) incurred in the war theaters of Iraq and Afghanistan is associated with the development of neuropsychiatric injuries (including post-traumatic stress disorder [PTSD] and major depression) among soldiers. Treatment for blast-related TBI is currently limited to counseling and palliative care. We have explored the effects of 74.5-kPa blast exposures that mimic mild TBI (mTBI) in a rat model. Blast- exposed rats exhibit a variety of PTSD-like behav... |