Treatment of the Chronic Blast-induced PTSD Phenotype with Capsaicin
Miguel A. Gama Sosa
Congressional District Code:
December 2020 -
FY 2021 Funding Amount:
Total Award Amount (all years):
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt:
Summary Blast-related traumatic brain injury (TBI) incurred in the war theaters of Iraq and Afghanistan is associated with the development of neuropsychiatric injuries (including post-traumatic stress disorder [PTSD] and major depression) among soldiers. Treatment for blast-related TBI is currently limited to counseling and palliative care. We have explored the effects of 74.5-kPa blast exposures that mimic mild TBI (mTBI) in a rat model. Blast- exposed rats exhibit a variety of PTSD-like behav...