Role of Complement Receptor 1 in the Modulation of B Cell Tolerance
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Clinical Science R&D
October 2020 -
FY 2021 Funding Amount:
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View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt:
Autoimmune diseases affect more than 2% of the US population, with effects on morbidity and mortality and associated health care costs that rival those of cancer and heart disease. Both genetic and environmental factors influence the development of autoimmune diseases, which result from an imbalance between activation and regulation of the immune system. As our understanding of the immunological mechanisms that drive these diseases has grown, the impetus has been to develop specific therapies th...