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Project Number: | I01CX002011-01A1 |
| Title: | Accelerated Aging as a Cause of Chronic Lung Allograft Dysfunction |
| Principal Investigator: | John Greenland |
| Location: | San Francisco, CA |
| Congressional District Code: | 12 |
| Research Service: | Clinical Science R&D |
| Project Period: | July 2020 - June 2024 |
| FY 2021 Funding Amount: | $332,514 |
| Total Award Amount (all years): |
$1,225,788 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Lung transplantation is a lifesaving option for veterans with end-stage lung diseases, in particular idiopathic pulmonary fibrosis (IPF). Veterans appear to be disproportionately affected by IPF, a disease that has been described as early aging of the lung. IPF is usually fatal unless the lungs are replaced by transplant. Even following lung transplantation median survival is less than six years, limited primarily by chronic lung allograft dysfunction (CLAD). Emerging data suggest that telomeres... |