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Funded Project Details - FY2021




Project Number:

I01CX002062-01A1
Title: To explore the potential of UCH-L1 as a novel therapeutic and diagnostic target in heart failure
Principal Investigator:

Taixing Cui

Location: Columbia, SC
Congressional District Code: 2
Research Service: Clinical Science R&D
Project Period: April 2021 - March 2025
FY 2021 Funding Amount: $180,501
Total Award Amount
(all years):
$1,200,006
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Heart failure (HF) is the number one reason for admission among patients in the Veteran (VA) health system, consuming a significant portion of VA medical resources. However, the molecular mechanism of HF is poorly understood and the treatment of HF still remains at the level of controlling symptom and reducing risk factors without a cure. Hence, further research into developing pathogenic mechanism-specific novel therapies for HF is an urgent need. Our pilot studies have demonstrated that a deub...



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