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Project Number: | I01BX005221-01 |
| Title: | CMA: Network plasticity in acquired epileptogenesis |
| Principal Investigator: | Stelios Smirnakis |
| Location: | Boston, MA |
| Congressional District Code: | 7 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | January 2021 - December 2024 |
| FY 2021 Funding Amount: | $167,573 |
| Total Award Amount (all years): |
$709,912 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Project Summary/ Abstract: Temporal Lobe Epilepsy (TLE) is the most frequent type of post-traumatic epilepsy, causing significant morbidity in the veteran population. Approximately 60% of adult epilepsy cases are due to TLE, which is often medication-resistant requiring surgery. Even after surgery, ~30% of patients continue to have ictal events. TLE causes cognitive deficits, including significant executive, memory, and neuropsychiatric dysfunction. After initiation by a precipitating even... |