CMA: Network plasticity in acquired epileptogenesis
Congressional District Code:
Biomedical Laboratory R&D
January 2021 -
FY 2021 Funding Amount:
Total Award Amount (all years):
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt:
Project Summary/ Abstract: Temporal Lobe Epilepsy (TLE) is the most frequent type of post-traumatic epilepsy, causing significant morbidity in the veteran population. Approximately 60% of adult epilepsy cases are due to TLE, which is often medication-resistant requiring surgery. Even after surgery, ~30% of patients continue to have ictal events. TLE causes cognitive deficits, including significant executive, memory, and neuropsychiatric dysfunction. After initiation by a precipitating even...