Office of Research & Development |
  |
Talk to the Veterans Crisis Line now
An official website of the United States government
Project Number: | I01BX004870-01A1 |
| Title: | microRNA Regulation of The Cocaine Effects on the Cardiovascular System |
| Principal Investigator: | Chunming Dong |
| Location: | Miami, FL |
| Congressional District Code: | 24 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | October 2020 - September 2024 |
| FY 2021 Funding Amount: | $185,748 |
| Total Award Amount (all years): |
$688,948 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Despite the opioid overdose crisis, cocaine remains a widely abused illicit drug by the public and by veterans. While opioid overdose primarily causes respiratory failure, cocaine abuse is mainly associated with cardiovascular (CV) toxicities, which include hypertension (HTN), aortic stiffness, and atherosclerosis. Indeed, cocaine abuse represents a significant CV risk for the general population and for veterans. It is known that cocaine stimulates the sympathetic nervous system (SNS) by inhibit... |