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Project Number: | I01BX004828-01A1 |
| Title: | Molecular and Cellular Dissection of miRNAs in Controlling Allergic Airway Inflammation in Mice |
| Principal Investigator: | David B. Corry |
| Location: | Houston, TX |
| Congressional District Code: | 9 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | July 2020 - June 2024 |
| FY 2021 Funding Amount: | $206,800 |
| Total Award Amount (all years): |
$701,800 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: The long-term objective of our laboratory is to understand the underlying molecular and genetic causes for chronic allergic airway inflammation or asthma to improve therapeutic approaches. The specific objective of this application is to dissect microRNA (miRNA)-dependent inflammatory pathways in dendritic cells (DCs) and CD4+ T cells that modulate murine allergic airway disease to fungal allergens. Asthma is a major rising global health threat that disproportionately affects combat veterans. We... |