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Project Number: | I01BX002690-05A2 |
| Title: | Analysis of a Type I Interferon Responsive Microglia Subset in Traumatic Brain Injury |
| Principal Investigator: | Christine L Hsieh |
| Location: | San Francisco, CA |
| Congressional District Code: | 12 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | October 2020 - October 2024 |
| FY 2021 Funding Amount: | $321,281 |
| Total Award Amount (all years): |
$1,615,589 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: TBI is a major cause of disability and a significant burden to health care costs in the US. TBI management lacks effective pharmacological treatment. Neuroinflammation is a component of secondary injury that can worsen brain injury, and it progresses over time, thus allowing opportunities to pharmacologically intervene. The goal of this project is to better understand a novel microglia subset in TBI, and determine whether it is a cellular mechanism driving pathology in TBI. We hope that knowledg... |