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Funded Project Details - FY2021

Project Number:

Title: Analysis of a Type I Interferon Responsive Microglia Subset in Traumatic Brain Injury
Principal Investigator:

Christine L Hsieh

Location: San Francisco, CA
Congressional District Code: 12
Research Service: Biomedical Laboratory R&D
Project Period: October 2020 - October 2024
FY 2021 Funding Amount: $321,281
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


TBI is a major cause of disability and a significant burden to health care costs in the US. TBI management lacks effective pharmacological treatment. Neuroinflammation is a component of secondary injury that can worsen brain injury, and it progresses over time, thus allowing opportunities to pharmacologically intervene. The goal of this project is to better understand a novel microglia subset in TBI, and determine whether it is a cellular mechanism driving pathology in TBI. We hope that knowledg...

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