Office of Research & Development |
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Project Number: | I01BX001075-08 |
Title: | Neurovascular signaling and associated forebrain circuits in PTSD |
Principal Investigator: | Renu Sah |
Location: | Cincinnati, OH |
Congressional District Code: | 1 |
Research Service: | Biomedical Laboratory R&D |
Project Period: | October 2020 - September 2024 |
FY 2021 Funding Amount: | $274,639 |
Total Award Amount (all years): |
$1,273,105 |
Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Posttraumatic Stress Disorder (PTSD) is a disabling psychiatric condition that is highly prevalent in combat veterans. Only a fraction of trauma-exposed individuals develop PTSD, suggesting that pre-existing neurobiological factors contribute to susceptibility/ risk. Currently, specific molecular/ circuit-level mechanisms that contribute to PTSD risk are not well-defined. Substantial information supports that pre-existing dysfunction in fear circuits may promote vulnerability to PTSD, however me... |