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Project Number: | I01RX003415-01 |
| Title: | Romosozumab to Improve Bone Mineral Density and Architecture in Chronic SCI |
| Principal Investigator: | William A. Bauman |
| Location: | Bronx, NY |
| Congressional District Code: | 13 |
| Research Service: | Rehabilitation R&D |
| Project Period: | June 2020 - May 2024 |
| FY 2021 Funding Amount: | $273,622 |
| Total Award Amount (all years): |
$1,042,636 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Persons with chronic spinal cord injury (SCI) have markedly reduced bone mass and the loss of skeletal architectural integrity, which predisposes them to low-impact fractures. Currently, there is no practical treatment to reverse the severe bone loss in persons with chronic SCI. In the proposed study, a dual pharmacological intervention will be tested to improve bone health. Restoration of bone mass below the level of injury would be expected to reduce the morbidity associated with fractures and... |