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Funded Project Details - FY2021

Project Number:

Title: Nitrous Oxide for Posttraumatic Stress Disorder (PTSD): A Phase IIa Trial
Principal Investigator:

Carolyn Rodriguez

Location: Palo Alto, CA
Congressional District Code: 18
Research Service: Clinical Science R&D
Project Period: July 2020 - June 2024
FY 2021 Funding Amount: $150,524
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Post-traumatic stress disorder (PTSD) seriously disrupts the lives of many Veterans. Current first-line treatments, serotonin reuptake inhibitors or prolonged exposure therapy, take weeks to months to bring meaningful improvement, leaving Veterans experiencing prolonged suffering. A promising new treatment approach for rapidly reducing PTSD symptoms is nitrous oxide, an inhalation anesthetic and putative N-methyl-D-aspartate receptor (NMDAR) modulator that diminishes depression symptoms within 1...

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