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Funded Project Details - FY2021




Project Number:

I01CX001980-01A1
Title: Reward processing and depressive subtypes: Identifying neural biotypes related to suicide risk, resilience, and treatment response
Principal Investigator:

Susanna L Fryer

Location: San Francisco, CA
Congressional District Code: 12
Research Service: Clinical Science R&D
Project Period: October 2020 - September 2024
FY 2021 Funding Amount: $132,749
Total Award Amount
(all years):
$979,570
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Anhedonia and amotivation are common in depressive presentations, and putatively thought to be caused by alterations in the ways in which the brain anticipates, evaluates, and adaptively uses reward-related information. However, reward processing is a complex, multi-circuit phenomenon, and the precise neural mechanisms that contribute to the absence or reduction of typical hedonic and motivational outputs seen in the clinic are still being elucidated. Heterogeneity in the clinical presentation o...



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