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Project Number: | I01BX004713-01A1 |
| Title: | Investigating the IL-4/13 Axis in Osteoarthritis |
| Principal Investigator: | William H. Robinson |
| Location: | Palo Alto, CA |
| Congressional District Code: | 18 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | January 2020 - December 2023 |
| FY 2021 Funding Amount: | $141,800 |
| Total Award Amount (all years): |
$650,000 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Many Veterans and civilians sustain traumatic joint injuries, which frequently lead to joint dysfunction and development of osteoarthritis (OA). Existing treatments for joint injury and OA only alleviate symptoms, and are ineffective in promoting healing or preventing OA. Increasing evidence implicates “low-grade” inflammation following joint injury in development of OA. A better understanding of the underlying inflammatory mechanisms and identification of pharmacologic agents that target these... |