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Funded Project Details - FY2021




Project Number:

I01BX004944-01
Title: Impact of Inflammatory Pathway in Tumor Stroma on Pancreatic Cancer Growth
Principal Investigator:

Vikas Dudeja

Location: Birmingham, AL
Congressional District Code: 24
Research Service: Biomedical Laboratory R&D
Project Period: April 2020 - March 2024
FY 2021 Funding Amount: $106,800
Total Award Amount
(all years):
$710,000
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Despite recent advances, pancreatic cancer patients continue to have dismal outcomes thereby underscoring the need for development of new therapeutic strategies. Recently, there has been a resurgence in understanding the role played by stroma in supporting tumor growth and the stroma- cancer cell cross talk continues to be a promising anti-cancer target. Previous research has shown that NFκB, the master regulator of inflammation, is overexpressed in various cancer cells, and its deletion in the...



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