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Funded Project Details - FY2021

Project Number:

Title: Impact of Inflammatory Pathway in Tumor Stroma on Pancreatic Cancer Growth
Principal Investigator:

Vikas Dudeja

Location: Birmingham, AL
Congressional District Code: 24
Research Service: Biomedical Laboratory R&D
Project Period: April 2020 - March 2024
FY 2021 Funding Amount: $106,800
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Despite recent advances, pancreatic cancer patients continue to have dismal outcomes thereby underscoring the need for development of new therapeutic strategies. Recently, there has been a resurgence in understanding the role played by stroma in supporting tumor growth and the stroma- cancer cell cross talk continues to be a promising anti-cancer target. Previous research has shown that NFκB, the master regulator of inflammation, is overexpressed in various cancer cells, and its deletion in the...

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