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Project Number: | I01BX004658-01A1 |
| Title: | The Multiple Roles of Lysyl Oxidase in Arteriovenous Fistula Failure |
| Principal Investigator: | Roberto Vazquez-Padron |
| Location: | Miami, FL |
| Congressional District Code: | 24 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | April 2020 - March 2024 |
| FY 2021 Funding Amount: | $239,648 |
| Total Award Amount (all years): |
$1,127,179 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: More than 14 000 enrolled veterans depend on an arteriovenous (A-V) fistula or other type of vascular access to receive hemodialysis and prolong their lives. The transformation of a vein to a fistula is one of the most intriguing processes in vascular biology. The desired scenario is that the fistula matures becoming a larger vessel with increased luminal area and a thicker wall. Unfortunately, A-V fistulas frequently fail (~40%) because venous stenosis compromises blood flow. We recently discov... |