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Project Number: | I01BX004975-01 |
| Title: | The effect of adventitial vein cells on vein graft neointimal hyperplasia |
| Principal Investigator: | Gale Tang |
| Location: | Seattle, WA |
| Congressional District Code: | 9 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | January 2020 - December 2023 |
| FY 2021 Funding Amount: | $156,800 |
| Total Award Amount (all years): |
$685,130 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Veterans are disproportionately affected by peripheral artery disease (PAD) and coronary artery disease (CAD) because of high rates of tobacco use in the veteran population. Up to one-third of the saphenous vein bypass grafts performed for either PAD or CAD fail secondary to a process called neointimal hyperplasia. We have established a new model to study saphenous vein grafts by implanting human saphenous veins into immunodeficient nude rats. This model develops significant neointimal hyperplas... |