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Funded Project Details - FY2021

Project Number:

Title: The effect of adventitial vein cells on vein graft neointimal hyperplasia
Principal Investigator:

Gale Tang

Location: Seattle, WA
Congressional District Code: 9
Research Service: Biomedical Laboratory R&D
Project Period: January 2020 - December 2023
FY 2021 Funding Amount: $156,800
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Veterans are disproportionately affected by peripheral artery disease (PAD) and coronary artery disease (CAD) because of high rates of tobacco use in the veteran population. Up to one-third of the saphenous vein bypass grafts performed for either PAD or CAD fail secondary to a process called neointimal hyperplasia. We have established a new model to study saphenous vein grafts by implanting human saphenous veins into immunodeficient nude rats. This model develops significant neointimal hyperplas...

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