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Funded Project Details - FY2021

Project Number:

Title: Surgical Studies on Mucosal Homeostasis
Principal Investigator:

Rao N. Jaladanki

Location: Baltimore, MD
Congressional District Code: 7
Research Service: Biomedical Laboratory R&D
Project Period: April 2020 - March 2024
FY 2021 Funding Amount: $258,439
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Patients with critical surgical disorders such as trauma, thermal injury, shock, sepsis, and massive surgical operations are commonly complicated with acute gut mucosal injury and bleeding. Disruption of the gut epithelial integrity causes sepsis and in some instances acts as the trigger that drives multiple organ dysfunction syndrome (MODS), a leading cause of death in critically ill patients. Effective therapies to enhance mucosal defense and promote epithelial repair after acute injury in pat...

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