Office of Research & Development |
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Project Number: | I01BX002565-05 |
Title: | Attenuating microglial-dependent axonal pathology in EAE |
Principal Investigator: | Jeffrey Dupree |
Location: | Richmond, VA |
Congressional District Code: | 3 |
Research Service: | Biomedical Laboratory R&D |
Project Period: | April 2020 - March 2024 |
FY 2021 Funding Amount: | $258,010 |
Total Award Amount (all years): |
$1,200,297 |
Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Project Summary: Nearly 30,000 US veterans are in the VA system being treated for Multiple Sclerosis (MS), a disabling disease that results in motor, sensory and cognitive dysfunction. There is no cure and treatments have limited efficacy. The overall goal of my lab is to provide a better understanding of the pathologic mechanisms that drive MS in order to develop new and better treatment options. MS is classically described as a demyelinating disorder where myelin loss is accompanied by axonal... |