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Funded Project Details - FY2021

Project Number:

Title: Deconstructing Spasticity after Spinal Cord Injury
Principal Investigator:

Andrew Tan

Location: West Haven, CT
Congressional District Code: 3
Research Service: Rehabilitation R&D
Project Period: October 2019 - September 2023
FY 2021 Funding Amount: $292,743
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


The goal of this study is to investigate the cellular and molecular mechanisms underlying spasticity, and establish the groundwork for future translational studies in the clinic. A majority of US Veterans with SCI experience clinically significant spasticity, which can disrupt rehabilitation and negatively impact quality-of-life, e.g., mobility, personal hygiene, intimate relationships (Holtz et al., 2017; Skold et al., 1999; Walter et al., 2002). Current spasticity management strategies are pal...

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