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Funded Project Details - FY2021




Project Number:

I01CX001999-01
Title: Targeting Oxidative Stress to Prevent Vascular and Skeletal Muscle Dysfunction during Disuse
Principal Investigator:

Joel D Trinity

Location: Salt Lake City, UT
Congressional District Code: 2
Research Service: Clinical Science R&D
Project Period: July 2019 - June 2023
FY 2021 Funding Amount: $281,879
Total Award Amount
(all years):
$1,045,249
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Disuse following injury, illness, or surgery is linked to functional deficiencies, hospital readmission, impaired recovery, and increased mortality. Older Veterans are particularly vulnerable to disuse as functional (vascular and skeletal muscle mitochondrial dysfunction) and structural (loss in muscle mass and strength) deficits are present as a consequence of the aging process. The accelerated declines that occur during disuse further deplete an already diminished physiological and functional...



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