Office of Research & Development |
  |
Talk to the Veterans Crisis Line now
An official website of the United States government
Project Number: | I01CX001999-01 |
| Title: | Targeting Oxidative Stress to Prevent Vascular and Skeletal Muscle Dysfunction during Disuse |
| Principal Investigator: | Joel D Trinity |
| Location: | Salt Lake City, UT |
| Congressional District Code: | 2 |
| Research Service: | Clinical Science R&D |
| Project Period: | July 2019 - June 2023 |
| FY 2021 Funding Amount: | $281,879 |
| Total Award Amount (all years): |
$1,045,249 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Disuse following injury, illness, or surgery is linked to functional deficiencies, hospital readmission, impaired recovery, and increased mortality. Older Veterans are particularly vulnerable to disuse as functional (vascular and skeletal muscle mitochondrial dysfunction) and structural (loss in muscle mass and strength) deficits are present as a consequence of the aging process. The accelerated declines that occur during disuse further deplete an already diminished physiological and functional... |