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Funded Project Details - FY2021

Project Number:

Title: Development of Potent Inhibitors of proto-oncogene PELP1 for Treating Advanced Breast Cancer
Principal Investigator:

Ratna Vadlamudi

Location: San Antonio, TX
Congressional District Code: 21
Research Service: Biomedical Laboratory R&D
Project Period: October 2019 - September 2023
FY 2021 Funding Amount: $258,296
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Project summary Breast cancer (BCa) is the second leading cause of cancer death in women. Among Servicewomen, BCa is the most commonly diagnosed cancer, accounting for 30% of female cancers with increased prevalence in older Veterans. BCa has distinct molecular subtypes; estrogen receptor (ER) positive and triple negative breast cancer (TNBC). A significant portion of ER-positive BCa initially respond to anti-estrogens or aromatase inhibitors but eventually exhibit unresponsiveness to therapy, d...

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