Improving Outcomes in Veterans with Heart Failure and Chronic Kidney Disease
Congressional District Code:
Health Services R&D
April 2019 -
FY 2021 Funding Amount:
Total Award Amount (all years):
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt:
Project Summary Heart failure (HF) is a major public health problem with high mortality (~50% at 5 years) and hospital readmission (~25% at 30 days). Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) improve both outcomes in patients with HF with reduced ejection fraction (HFrEF). However, these drugs also adversely affect kidney function, and may increase the risk of acute kidney injury (AKI), chronic kidney disease (CKD) progression, and incident kidney...