GVHD quantitative assessment in skin of Veterans post-HCT
Congressional District Code:
Clinical Science R&D
January 2019 -
FY 2021 Funding Amount:
Total Award Amount (all years):
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt:
Chronic graft-versus-host disease (cGVHD) is the leading cause of nonrelapse mortality following allogeneic hematopoietic stem cell transplantation (HCT). Once the diagnosis is made, a fundamental practice gap remains the determination of whether disease is stable or progressing. Clinical trials of promising new potential treatments are limited by the lack of reproducible and sensitive measures of cGVHD severity. Skin is central to cGVHD evaluation because it is the most commonly involved organ...