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Funded Project Details - FY2021




Project Number:

I01CX001837-01
Title: A Randomized Trial of Pioglitazone for the Treatment of Alcohol Use Disorder
Principal Investigator:

Eric W. Dieperink

Location: Minneapolis, MN
Congressional District Code: 5
Research Service: Clinical Science R&D
Project Period: April 2019 - March 2023
FY 2021 Funding Amount: $231,700
Total Award Amount
(all years):
$882,506
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Alcohol use Disorder (AUD) is common among Veterans and is associated with significant morbidity and mortality. In addition, the direct and indirect cost of AUD in Veterans is significant. Several FDA approved medications are available for the treatment of AUD and are thought to act through inhibitory and excitatory neuronal pathways including gamma-aminobutyric acid (GABA), glutamate and opioid pathways. However, effect sizes are generally small and they are used in a minority of patients. Thus...



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