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Project Number: | I01BX004352-01A1 |
| Title: | Influence of APOE genotypes on blood brain barrier transport of DHA by mfsd2a in Alzheimer's Disease |
| Principal Investigator: | Laila Abdullah |
| Location: | Tampa, FL |
| Congressional District Code: | 14 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | October 2019 - September 2023 |
| FY 2021 Funding Amount: | $185,724 |
| Total Award Amount (all years): |
$856,968 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Over 200,000 US Veterans are suffering from Alzheimer's disease (AD) and this figure is expected to increase dramatically in the next few decades due to a higher prevalence of traumatic brain injury (TBI) and post- traumatic stress disorder (PTSD) that are risk factors of AD among soldiers returning from Iraq and Afghanistan wars. The apolipoprotein E (APOE) ε4 allele is the most prevalent genetic risk factor for AD, representing 60% of AD subjects in the general population. The apoE protein is a... |