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Project Number: | I01BX004256-01A1 |
| Title: | Role of complement in TBI |
| Principal Investigator: | Stephen Tomlinson |
| Location: | Charleston, SC |
| Congressional District Code: | 1 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | January 2019 - December 2022 |
| FY 2021 Funding Amount: | $156,950 |
| Total Award Amount (all years): |
$964,475 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: After initial mechanical insult, traumatic brain injury (TBI) is characterized by a dynamic process of secondary injury that involves chronic neuroinflammation and which is implicated in long-term cognitive and motor impairments. It has long been recognized that neuroinflammation is injurious and represents a therapeutic target for treating TBI. The complement system is a central component of the inflammatory cascade, and while there is increasing evidence that complement plays an important role... |