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Project Number: | I01BX002348-05A2 |
| Title: | Cellular and Molecular Mechanisms of Renal Anemia |
| Principal Investigator: | Volker H Haase |
| Location: | Nashville, TN |
| Congressional District Code: | 5 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | January 2019 - December 2022 |
| FY 2021 Funding Amount: | $156,800 |
| Total Award Amount (all years): |
$710,000 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Advanced chronic kidney disease (CKD) and end stage renal disease (ESRD) are characterized by the inability of the diseased kidney to respond to hypoxia with adequate production of erythropoietin (EPO), the glycoprotein hormone that is essential for the generation of red blood cells, and is furthermore associated with absolute and functional iron deficiency. This leads to the development of anemia, a clinical hallmark of advanced CKD, which is typically treated with recombinant human EPO and int... |