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Project Number: | I01BX004045-01A2 |
| Title: | Investigation of therapeutic potential of exogenous ubiquitin following myocardial ischemia/reperfusion injury |
| Principal Investigator: | Krishna Singh |
| Location: | Mountain Home, TN |
| Congressional District Code: | 1 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | April 2019 - March 2024 |
| FY 2021 Funding Amount: | $87,059 |
| Total Award Amount (all years): |
$1,333,585 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Ischemic heart disease (IHD) is a leading cause of death among veterans. Myocardial infarction (MI) is a serious outcome of IHD, and is generally attributable to the detrimental effects of myocardial ischemia/reperfusion (I/R) injury. Cardiac inflammation and extracellular matrix deposition (scar formation) are essential events in the cardiac remodeling post-MI. Therapeutic approaches targeting these events may hold promise for patients with MI. This proposal investigates the therapeutic potenti... |