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Project Number: | I01BX004434-01 |
| Title: | Mechanisms regulating cytomegalovirus |
| Principal Investigator: | Jeffery L. Meier |
| Location: | Iowa City, IA |
| Congressional District Code: | 2 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | October 2018 - September 2022 |
| FY 2021 Funding Amount: | $156,800 |
| Total Award Amount (all years): |
$769,755 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Human cytomegalovirus (HCMV) infects over half of all Veterans and threatens the lives of those with impaired immune systems. Even among Veterans with normal immune systems, the insidious reactivation of the virus taxes the immune system, incites low-level inflammation, and possibly accelerates aging and shortens lifespan. HCMV is the most common infectious cause of birth defects. There is no HCMV vaccine and the antiviral drugs have problems with potency, toxicity, and drug-resistance. The long... |