Office of Research & Development |
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Project Number: | I01RX002660-01A2 |
Title: | Neurodegeneration following low-level blast exposure |
Principal Investigator: | Gregory A. Elder |
Location: | Bronx, NY |
Congressional District Code: | 13 |
Research Service: | Rehabilitation R&D |
Project Period: | October 2018 - September 2022 |
FY 2021 Funding Amount: | $370,775 |
Total Award Amount (all years): |
$1,194,281 |
Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Traumatic brain injury (TBI) is a risk factor for the development of neurodegenerative diseases in which cognitive impairment is prominent, including Alzheimer’s disease and chronic traumatic encephalopathy (CTE). The high prevalence of mild TBI (mTBI) due to blast exposure in the recent conflicts in Iraq and Afghanistan puts veterans at increased risk of these disorders. Interestingly, male rats exposed to repetitive low-level blast exposures exhibit a chronic behavioral phenotype that includes... |