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Funded Project Details - FY2021




Project Number:

I21RX002867-01
Title: Vocal cord tissue engineering: Pre-clinical scale-up
Principal Investigator:

Jennifer L Long

Location: West Los Angeles, CA
Congressional District Code: 33
Research Service: Rehabilitation R&D
Project Period: July 2018 - December 2020
FY 2021 Funding Amount: $0
Total Award Amount
(all years):
$199,178
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Veterans suffering loss of the larynx's vocal fold cover due to trauma or laryngeal cancer can suffer disabling voice difficulties, and treatment options are limited. A vibrating replacement tissue would revolutionize the treatment of laryngeal disorders. The work described in this proposal characterizes and optimizes a tissue-engineered Cell-based Outer Vocal cord Replacement (COVR). Adult human multipotent cells isolated from adipose tissue are cultured within fibrin hydrogel derived from the...



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