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Funded Project Details - FY2021

Project Number:

Title: Vocal cord tissue engineering: Pre-clinical scale-up
Principal Investigator:

Jennifer L Long

Location: West Los Angeles, CA
Congressional District Code: 33
Research Service: Rehabilitation R&D
Project Period: July 2018 - December 2020
FY 2021 Funding Amount: $0
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Veterans suffering loss of the larynx's vocal fold cover due to trauma or laryngeal cancer can suffer disabling voice difficulties, and treatment options are limited. A vibrating replacement tissue would revolutionize the treatment of laryngeal disorders. The work described in this proposal characterizes and optimizes a tissue-engineered Cell-based Outer Vocal cord Replacement (COVR). Adult human multipotent cells isolated from adipose tissue are cultured within fibrin hydrogel derived from the...

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