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Project Number: | I01BX004184-01A1 |
| Title: | Single nucleotide and copy number variants associated with Parkinson disease |
| Principal Investigator: | James Ashe |
| Location: | Minneapolis, MN |
| Congressional District Code: | 5 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | April 2019 - September 2022 |
| FY 2021 Funding Amount: | $78,400 |
| Total Award Amount (all years): |
$335,584 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: The Million Veteran Program (MVP) data set will be used to identify new genetic risk variants— including copy number variants (CNVs: deletions and duplications in the genome)—for Parkinson disease (PD). Previously identified genetic risk factors will be better characterized by testing all pairwise gene-by-gene interactions and testing if variants associated with mRNA expression levels are predictive of PD risk using PrediXcan. The MVP intake questionnaire captured previously identified environme... |