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Funded Project Details - FY2021

Project Number:

Title: Single nucleotide and copy number variants associated with Parkinson disease
Principal Investigator:

James Ashe

Location: Minneapolis, MN
Congressional District Code: 5
Research Service: Biomedical Laboratory R&D
Project Period: April 2019 - September 2022
FY 2021 Funding Amount: $78,400
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


The Million Veteran Program (MVP) data set will be used to identify new genetic risk variants— including copy number variants (CNVs: deletions and duplications in the genome)—for Parkinson disease (PD). Previously identified genetic risk factors will be better characterized by testing all pairwise gene-by-gene interactions and testing if variants associated with mRNA expression levels are predictive of PD risk using PrediXcan. The MVP intake questionnaire captured previously identified environme...

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