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Funded Project Details - FY2021




Project Number:

I01BX004184-01A1
Title: Single nucleotide and copy number variants associated with Parkinson disease
Principal Investigator:

James Ashe

Location: Minneapolis, MN
Congressional District Code: 5
Research Service: Biomedical Laboratory R&D
Project Period: April 2019 - September 2022
FY 2021 Funding Amount: $78,400
Total Award Amount
(all years):
$335,584
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

The Million Veteran Program (MVP) data set will be used to identify new genetic risk variants— including copy number variants (CNVs: deletions and duplications in the genome)—for Parkinson disease (PD). Previously identified genetic risk factors will be better characterized by testing all pairwise gene-by-gene interactions and testing if variants associated with mRNA expression levels are predictive of PD risk using PrediXcan. The MVP intake questionnaire captured previously identified environme...



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