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Funded Project Details - FY2021

Project Number:

Title: Hi-jacking the kynurenine pathway: A new path used by cisplatin resistant non-small cell lung cancer to survive and evade immune surveillance under high ROS
Principal Investigator:

Medhi Wangpaichitr

Location: Miami, FL
Congressional District Code: 24
Research Service: Biomedical Laboratory R&D
Project Period: July 2018 - June 2022
FY 2021 Funding Amount: $294,379
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


The toll of lung cancer deaths in the United States exceeds that of the next four major cancers combined, and is the most common cancer found in veterans. Not only is the incidence higher, but the survival is lower than in civilian populations. Surgery is the main treatment for early stage lung cancer, but most patients already have locally advanced or metastatic disease at the time of diagnosis. Subsequently, chemotherapy or combined chemotherapy with radiation therapy remains the primary modal...

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